The paper identifies the pangenomic origins and molecular basis of RMES1, a noncanonical NLR gene that enabled evolutionary rescue in sorghum by disrupting aphid feeding through global immunity activation.

Science Advances · Oct 10, 2025Peer-reviewedGenetics

The Arabidopsis TIRome informs the design of artificial TIR (Toll/interleukin-1 receptor) domain proteins

Adam M. Bayless, Lijiang Song, Mitchell Sorbello, Sam C. Ogden, Tyler S. Todd, Alice Flint, Natsumi Maruta, Jedidiah Tulu, Mikhail S. Drenichev, Vardis E. Ntoukakis, Thomas Ve, Mehdi Mobli, Li Wan, Qingli Liu, Jeffery L. Dangl, , Marc T. Nishimura

This study analyzes the TIRome of Arabidopsis to design artificial TIR proteins and identify functional polymorphisms that influence cell death and metabolite production.

Proceedings of the National Academy of Sciences · Sep 12, 2025Peer-reviewedPlant Biology

mRNA localization is linked to translation regulation in the Caenorhabditis elegans germ lineage

Dylan M. Parker, Lindsay P. Winkenbach, Samuel P. Boyson, Matthew Neeley Saxton, Camryn Daidone, Zainab Ali Al-Mazaydeh, Marc T. Nishimura, Florian Mueller, Erin Osborne Nishimura

The paper shows that mRNA localization to P granules in C. elegans embryos is linked to translational repression, not just a downstream effect.

Development · Jan 1, 2020Peer-reviewedDevelopmental Biology