Author

Melissa D. Zhang

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Gregory M. FindlayiD· 2 shared Jay ShendureiD· 2 shared Molly J. GasperiniiD· 2 shared Aaron McKennaiD· 1 shared Anh Leith· 1 shared Beth MartiniD· 1 shared Choli LeeiD· 1 shared Darren A. CusanovichiD· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Gregory M. FindlayORCID

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2 papers

Recent·Most cited

Accurate functional classification of thousands of BRCA1 variants with saturation genome editing

Gregory M. Findlay, Riza M. Daza, Beth Martin, Melissa D. Zhang, Anh Leith, Molly J. Gasperini, Joseph D. Janizek, Xingfan Huang, Lea M. Starita, Jay Shendure

The paper functionally classifies thousands of BRCA1 variants using saturation genome editing to determine their impact on cancer risk.

Nature · Sep 11, 2018Peer-reviewedGenomics

Paired CRISPR/Cas9 guide-RNAs enable high-throughput deletion scanning (ScanDel) of a Mendelian disease locus for functionally critical non-coding elements

Molly J. Gasperini, Gregory M. Findlay, Aaron McKenna, Jennifer H. Milbank, Choli Lee, Melissa D. Zhang, Darren A. Cusanovich, Jay Shendure

This paper introduces ScanDel, a CRISPR-based method to systematically delete non-coding regions of a gene locus, revealing that distal regulatory elements are not critical for HPRT1 function.

The American Journal of Human Genetics · Jul 14, 2017Peer-reviewedGenomics