Three-dimensional tissue stiffness mapping in the mouse embryo supports durotaxis during early limb bud morphogenesis
Min Sheng Zhu, Hirotaka Tao, Mohammad Samani, Mengxi Luo, Xian Wang, Sevan Hopyan, Yu Sun
The paper introduces a 3D magnetic device to measure tissue stiffness in mouse embryos, revealing an anterior stiffness gradient that guides cell movement during limb bud development.
Proceedings of the National Academy of Sciences · Feb 18, 2020Peer-reviewedDevelopmental Biology