Yu Sun

This study identifies mGlu2 as a mechanosensitive GPCR in vestibular hair cells essential for balance, distinct from its role in hearing.

The paper shows that fibronectin-dependent tissue stiffness controls durotaxis and cell rearrangements through a phase transition model in mouse limb bud mesoderm.

origamiFISH enables label-free, single-molecule detection of DNA origami nanostructures in cells and tissues, revealing cell-type and shape-specific uptake patterns at low concentrations.

The paper shows that stochastic fluctuations and entropy, not stiffness gradients, drive neural crest cell ingression in mice.

This study develops a YAP fusion reporter mouse line and uses live imaging to analyze YAP localization dynamics during mouse embryonic development.

The paper introduces a 3D magnetic device to measure tissue stiffness in mouse embryos, revealing an anterior stiffness gradient that guides cell movement during limb bud development.

The paper shows that oscillatory cortical forces drive 3D cell intercalations in the mouse mandibular arch, shaping embryonic structures through Wnt5a, YAP/TAZ, and PIEZO1.