Accurate de novo design of peptides from programming biophysical landscape
Mingyu Li, Yini Liu, Jie Zhong, Xinchao Shi, Jiqing Zheng, Kai Wang, Cui Yunxia, Chaoran Cheng, Shijin Li, Xiangzhe Kong, S W Li, Miaojie Xv, Chunhao Zhu, Xiaobing Lan, He Yang, , Jian Zhang
NeoPep designs functional peptides de novo using a deep-learning framework that models biophysical principles, achieving high hit rates and structural accuracy across diverse targets.
bioRxiv · Jun 9, 2026 · PreprintMolecular Biology