He Yang

This paper introduces a deep learning framework for identifying dynamic protein allosteric sites across different conformational states, achieving improved performance over existing methods.

NeoPep designs functional peptides de novo using a deep-learning framework that models biophysical principles, achieving high hit rates and structural accuracy across diverse targets.

This paper develops a deep learning system to design multitarget antipsychotic drugs, generating novel compounds with activity against multiple receptors and demonstrating efficacy in animal models.