Brain Infiltrated Monocyte-Macrophages in a rat model of Temporal Lobe Epilepsy: Revisiting the Pro-Inflammatory Paradigm
Wanda Grabon, Nadia Gasmi, Anatole Lang, Anne Ruiz, Béatrice Georges, Victor Blot, Michaël Ogier, Sylvain Rheims, Fabrice P. Navarro, Laurent Bezin
The paper tracks monocyte infiltration and phenotypic changes in a rat epilepsy model, showing they adopt a microglia-like phenotype and sustain low-grade inflammation during chronic epilepsy.
Frontiers in Immunology · Dec 9, 2025Peer-reviewedNeuroscience