COSMIC-dFBA: A novel multi-scale hybrid framework for bioprocess modeling
Saratram Gopalakrishnan, William Johnson, Miguel Á. Valderrama-Gómez, Elçin Içten, Jasmine Tat, Michael Ingram, Coral Fung Shek, Pik Kay Chan, Fabrice Schlegel, Pablo A. Rolandi, Cleo Kontoravdi, Nathan E. Lewis
COSMIC-dFBA predicts cell density, antibody titer, and metabolite concentrations in bioreactors by integrating machine learning with genome-scale metabolic models.
Metabolic Engineering · Feb 20, 2024Peer-reviewedSystems Biology