Cancer BiologyMolecular Biology of the CellPeer-reviewed
DNA damage-induced PARP/ALC1 activation leads to Epithelial-to-Mesenchymal transition stimulating homologous recombination.
Fatemeh Rajabi, Rebecca Smith, Win-Yan Liu-Bordes…·Arturo Londoño‐Vallejo
This study shows DNA damage activates PARP and ALC1 to induce EMT, which enhances DNA repair via RAD51, and PARP inhibitors block this process.
10 citations