Author

Michael L. Klein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Marina A. Kasimova· 2 shared Aysenur Torun Yazici· 1 shared Daniel Sigg· 1 shared Daniele GranataiD· 1 shared Lucie Delemotte· 1 shared Mounir Tarek· 1 shared Tibor Rohacs· 1 shared Vincenzo CarnevaleiD· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

Marina A. Kasimova

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2 papers

Recent·Most cited

A consistent picture of TRPV1 activation emerges from molecular simulations and experiments

Marina A. Kasimova, Aysenur Torun Yazici, Yevgen Yudin, Daniele Granata, Michael L. Klein, Tibor Rohacs, Vincenzo Carnevale

The paper proposes a molecular mechanism for TRPV1 activation through conformational changes and validates it with bioinformatics, structural analysis, and experimental data.

bioRxiv · Aug 24, 2018 · PreprintBiophysics

Exploring the Complex Dynamics of an Ion Channel Voltage Sensor Domain via Computation

Lucie Delemotte, Marina A. Kasimova, Daniel Sigg, Michael L. Klein, Vincenzo Carnevale, Mounir Tarek

This study uses molecular dynamics simulations to bridge electrophysiology and molecular dynamics by predicting gating currents and confirming the role of rate-limiting barriers in VSD activation.

bioRxiv · Feb 16, 2017 · PreprintBiophysics