A consistent picture of TRPV1 activation emerges from molecular simulations and experiments
Marina A. Kasimova, Aysenur Torun Yazici, Yevgen Yudin, Daniele Granata, Michael L. Klein, Tibor Rohacs, Vincenzo Carnevale
The paper proposes a molecular mechanism for TRPV1 activation through conformational changes and validates it with bioinformatics, structural analysis, and experimental data.
bioRxiv · Aug 24, 2018 · PreprintBiophysics