Engineered Extracellular Vesicles Enriched with the miR-214/199a Cluster Enhance the Efficacy of Chemotherapy for Ovarian Cancer
Weida Wang, Ayesha B. Alvero, Yi Qin, Mingjin Wang, Alexandra Lucienne Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xianshuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang
This paper shows engineered extracellular vesicles carrying miR-214-3p/miR-199a-5p enhance chemotherapy effectiveness in ovarian cancer by reversing chemoresistance and reprogramming tumor EV communication.
Molecular Oncology · Feb 13, 2026Peer-reviewedCancer Biology