Scalable transcription factor mapping uncovers the regulatory dynamics of natural and synthetic transcription factors in human T cell states
Riley D. Z. Mullins, Jesse Meir Zaretsky, Emily Stoller, Michael Moore, Oliver Takacsi-Nagy, Oleg Shpynov, Remi Sampaleanu, Theodore L. Roth, Ansuman T. Satpathy, Robi David Mitra, Sidharth V. Puram
The paper develops and applies a scalable method to map transcription factor binding in human T cells, revealing novel regulatory dynamics and gene targets.
bioRxiv · Oct 9, 2025 · PreprintImmunology