Retinitis pigmentosa associated mutations in mouse Prpf8 cause misexpression of circRNAs and degeneration of cerebellar granule neurons
Michaela Krausová, Michaela Kreplová, Poulami Banik, Jan Kubovčiak, Martin Modrák, Dagmar Zudová, Jiří Lindovský, Agnieszka Kubik‐Zahorodna, Marcela Pálková, Michal Kolář, Jan Procházka, Radislav Sedláček, David Staněk
This study shows that mutations in Prpf8 in mice lead to misexpression of circRNAs and cerebellar granule neuron degeneration.
bioRxiv · Nov 1, 2022 · PreprintNeuroscience