The Centrosome Controls the Number and Spatial Distribution of Microtubules by Negatively Regulating Alternative MTOCs
Maria P. Gavilan, Pablo Gandolfo, Fernando R. Balestra, Francisco Arias, Michel Bornens, Rosa M. Rios
This study shows the centrosome regulates microtubule nucleation by both nucleating microtubules and inhibiting alternative MTOCs, leading to controlled microtubule density and spatial distribution.
bioRxiv · Jun 21, 2017 · PreprintCell Biology