Author

Michele M. Kyle

SUNY Upstate Medical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Li‐Ru ZhaoiD· 3 shared Heng HuiD· 1 shared Junchi HeiD· 1 shared Karen Hughes· 1 shared Lawrence S. ChiniD· 1 shared Robert S. GardneriD· 1 shared Shinichi KohsakaiD· 1 shared Songruo Li· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersNeuroscience

Li‐Ru ZhaoORCID

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3 papers

Recent·Most cited

Hematopoietic growth factors Regulate Entry of Monocytes into the Adult Brain via Chemokine Receptor CCR5

Xuefang Sophie Ren, Junchi He, Songruo Li, Heng Hu, Michele M. Kyle, Shinichi Kohsaka, Li‐Ru Zhao

This study shows that SCF and G-CSF enhance monocyte adhesion to brain endothelial cells via CCR5, facilitating their entry into the adult brain to replenish perivascular macrophages.

International Journal of Molecular Sciences · Aug 15, 2024Peer-reviewedNeuroscience

Single cell RNA sequencing reveals immunomodulatory effects of stem cell factor and granulocyte colony-stimulating factor treatment in the brains of aged APP/PS1 mice

Robert S. Gardner, Michele M. Kyle, Karen Hughes, Li‐Ru Zhao

This study uses single-cell RNA sequencing to show SCF+G-CSF treatment modulates microglia and myeloid cells in aged APP/PS1 mice, enhancing immune responses and Aβ clearance.

Biomolecules · Jul 10, 2024Peer-reviewedNeuroscience

Stem cell factor and granulocyte colony-stimulating factor promote remyelination in the chronic phase of severe traumatic brain injury

Xuecheng Qiu, Suning Ping, Michele M. Kyle, Lawrence S. Chin, Li‐Ru Zhao

This study shows that SCF+G-CSF treatment enhances remyelination in the chronic phase of severe TBI by promoting oligodendrocyte progenitor cell proliferation.

Cells · Feb 23, 2023Peer-reviewedNeuroscience