Balancing of immune activation and suppression during phage infection
Iana Fedorova, Yourun Yue, Zirui Gao, Michelle Grunberg, H Wang, Junjie Li, Zhiyu Zang, Diego De Nault, Xilin Yang, Joseph P. Gerdt, Yue Feng, Joseph Bondy‐Denomy
The paper shows how phages evade bacterial immune systems by using allelic variation and an anti-defense hotspot, revealing a similarity to a human protein.
bioRxiv · Jun 5, 2026 · PreprintMicrobiology