Standardizing the mouse MCAO Stroke Model: Distinguishing Internal Carotid vs Pterygopalatine Artery Occlusion
Ayman Isbatan, Samuel Lee, Frederick C. Damen, Sunny Chen, Michelle Malson, Xiaoping Du, Richard D. Minshall, Kejia Cai, Jiwang Chen
This study standardizes the mouse MCAO stroke model by distinguishing ICA and PPA occlusion, showing 15-minute ICA occlusion balances infarction and survival best.
bioRxiv · Oct 20, 2025 · PreprintPhysiology