Maladaptive cue-controlled cocaine-seeking habits promote increased relapse severity in rats.
Maxime Fouyssac, Yolanda Peña‐Oliver, Mickaёl Puaud, Nicole T Y Lim, Chiara Giuliano, Barry J. Everitt, David Belin
This study shows that rats with long-term cocaine-seeking habits controlled by cues show increased relapse severity, driven by negative urgency and striatal system interactions.
bioRxiv · Feb 1, 2021 · PreprintNeuroscience