David Belin

This study shows that serial processing between insular and prefrontal cortices determines risk-taking behavior in rats, with parallel processing linked to suboptimal decisions.

This study shows that sign-tracking rats develop compulsive drinking behaviors, which are worsened by chronic atomoxetine, suggesting a role for noradrenergic mechanisms in compulsive coping.

The paper shows that cocaine exposure reduces dopamine transporter levels in striatal astrocytes, with compulsive cocaine-seeking habits linked to reduced DAT mRNA in the nucleus accumbens shell.

This study shows pramipexole reduces impulsivity in highly impulsive rats by modulating frontostriatal networks, specifically through Zif268 mRNA downregulation in the nucleus accumbens core.

The paper identifies neurobehavioral markers in rats that predict future compulsive cocaine seeking behavior through pre-existing functional and structural brain changes.

The paper develops a machine-learning classifier to identify resilient or vulnerable rats in addiction-like behavior studies, showing high accuracy across different cohorts.

This study shows that compulsive coping behaviors in rats develop through dopamine-dependent mechanisms in the dorsolateral striatum after prolonged adjunctive drinking.

The paper identifies a correlation between low Arc mRNA levels in specific locus coeruleus neurons and the development of compulsive polydipsic drinking in rats.

This study shows that rats with long-term cocaine-seeking habits controlled by cues show increased relapse severity, driven by negative urgency and striatal system interactions.

The paper shows baclofen reduces compulsive alcohol drinking in rats with low GAT-3 mRNA in the central amygdala.

This study shows chronic glucocorticoid exposure impairs decision-making and cognitive functions in mice, with associated neurobiological changes in the prefrontal cortex.

This study shows that environmental conditions and experiential factors influence addiction vulnerability by affecting behavioral resilience and the context of drug use.

This study shows that direct projections from the basolateral amygdala to the nucleus accumbens core are required for cue-controlled cocaine seeking behavior.

This study shows that anterior insular cortex lesions after heroin exposure increase loss of control and relapse, contrasting with cocaine findings.