A Hollow TFG Condensate Spatially Compartmentalizes the Early Secretory Pathway
Savannah M Bogus, William R. Wegeng, Miguel Ruiz, Sindy R. Chavez, Samantha N Cheung, Khalid S. M. Noori, Ingrid R. Niesman, Andreas Max Ernst
The paper shows that TFG forms a hollow condensate at the ER-Golgi interface, acting as a molecular sieve that separates anterograde and retrograde carriers.
Nature Communications · Apr 19, 2025Peer-reviewedCell Biology