Differential quantitative requirements for pre-mRNA splicing-regulated shelterin protein levels in distinct telomere functions
Miho Takeuchi, Yoko Otsubo, Junko Kanoh
The paper shows that pre-mRNA splicing of shelterin proteins Rap1 and Poz1 is critical for telomere maintenance, with different telomere functions requiring varying levels of these proteins.
bioRxiv · Sep 2, 2025 · PreprintMolecular Biology