MCAK/Kif2C centromeric activity level tunes K-fiber turnover through distinct pathways.
Mike Wagenbach, Juan Jesus Vicente, Linda G. Wordeman
This paper shows that both excess and insufficient MCAK/Kif2C levels disrupt k-fiber turnover and increase chromosome segregation errors by altering tubulin ratios and MT interactions at kinetochores.
iScience · May 26, 2026Peer-reviewedCell Biology