Machine learning applied to whole-blood RNA-sequencing data uncovers distinct subsets of patients with systemic lupus erythematosus
William A. Figgett, Katherine Monaghan, Milica Ng, Monther Alhamdoosh, Eugene Maraskovsky, Nicholas J. Wilson, Alberta Yik-Bun Hoi, Eric Francis Morand, Fabienne Mackay
This paper uses machine learning on whole-blood RNA-seq data to stratify SLE patients into clusters, revealing gene expression patterns linked to disease activity and clinical outcomes.
Clinical & Translational Immunology · Jan 1, 2019Peer-reviewedBioinformatics