Author

Malcolm J. McConville

The University of Melbourne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:metabolomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alessandro D. Uboldi· 1 shared Alexandra L. GarnhamiD· 1 shared Amalie A Jaywickrama· 1 shared Amber Simonpietri· 1 shared Christopher J. TonkiniD· 1 shared David KomanderiD· 1 shared Eleanor C. Saunders· 1 shared Karan Singh· 1 shared

Activity by Year

2016-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

Alessandro D. Uboldi

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2 papers

Recent·Most cited

Differentiation of Toxoplasma into latent forms is linked to central carbon metabolism and requires a GID/CTLH-type E3 ubiquitin ligase

Alessandro D. Uboldi, Sachin Khurana, Amalie A Jaywickrama, Sai Prasanna Lekkala-Lethakula, Amber Simonpietri, Karan Singh, Vinzenz Hofferek, Ushma Ruparel, Lachlan L Whitehead, Kelly L. Rogers, Alexandra L. Garnham, Nichollas E. Scott, Nicholas J. Katris, Malcolm J. McConville, David Komander, , Christopher J. Tonkin

This study identifies glucose-limiting conditions and a GID/CTLH-type E3 ubiquitin ligase as key factors in Toxoplasma differentiation into latent forms.

bioRxiv · Jul 27, 2025 · PreprintMicrobiology

13C metabolic flux ratio analysis by direct measurement of free metabolic intermediates in L. mexicana using gas chromatography-mass spectrometry

Milica Ng, Eleanor C. Saunders, Moshe Olshansky, Malcolm J. McConville, Vladimir A. Likić

This paper introduces a new 13C-based metabolic flux analysis method for Leishmania mexicana using isotopologue analysis of free metabolites, enabling quantitative in vivo flux ratio calculations in human parasites.

bioRxiv · Sep 8, 2016 · PreprintSystems Biology