A rigorous benchmarking of alignment-based HLA callers for RNA-seq data
Dottie Yu, Ram Ayyala, Sarah Hany Sadek, Likhitha Chittampalli, Hafsa Farooq, Junghyun Jung, Abdullah Al Nahid, Grigore Boldirev, Mina Jung, Sung‐Min Park, Austin Nguyen, Alex Zelikovsky, Nicholas Mancuso, Jong Wha J. Joo, Reid F. Thompson, , Serghei Mangul
This study benchmarks 12 HLA callers on RNA-seq data across 682 samples to evaluate accuracy, computational cost, and performance differences by ancestry.
bioRxiv · May 22, 2023 · PreprintBioinformatics