Austin Nguyen

This study benchmarks 12 HLA callers on RNA-seq data across 682 samples to evaluate accuracy, computational cost, and performance differences by ancestry.

The paper evaluates four MHC binding affinity prediction tools across different peptide sources and alleles, revealing inconsistencies in their predictions and training data quality.

This study examines the association between HLA genotype and SARS-CoV-2 disease severity in 3,235 individuals, finding limited impact compared to demographic and clinical factors.

The paper introduces DIA-norm, a dynamic pathway analysis tool for time-course data, and shows it identifies more biologically relevant pathways than DAVID while demonstrating pigs as a better model for human adipogenesis than mice.

neoepiscope improves neoepitope prediction by incorporating germline context and somatic variant phasing, addressing limitations in existing tools.