Complement C3 recognition by C3 convertases
Changhao Jia, Xiaoke Yang, Ming-hui Zhao, Ying Cong Ryan Shea Tan, Junyu Xiao
The paper presents cryo-EM structures of complement convertases and their complexes to elucidate the molecular mechanisms of C3 recognition and activation in the classical and alternative pathways.
Science Advances · Feb 20, 2026Peer-reviewedMolecular Biology