High-resolution MRI Guided Whole Mouse Brain Cell Type Atlas using Deep Learning
Xinyue Han, Rui Hu, Zhuoheng Liu, Jie Chen, Mubashir Jafry, Haoyu Song, Yi Zhao, Mingquan Lin, LEONARD E. WHITE, G. Allan Johnson, Nian Wang
This paper develops a deep learning framework combining high-resolution MRI and spatial transcriptomics to create a whole-brain mouse cell type atlas at 10 micrometer resolution.
bioRxiv · Nov 25, 2025 · PreprintNeuroscience