Author

Jie Chen

Advanced Imaging Research (United States)ORCID 0000-0002-0110-1706Unclaimed ORCID profile · follow to get notified of new preprints

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Jie Chen15 papers · Nanjing Agricultural University

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1 Assay:multiome· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Nian WangiD· 2 shared Arupratan DasiD· 1 shared G. Allan JohnsoniD· 1 shared Haoyu Song· 1 shared LEONARD E. WHITEiD· 1 shared Lilesh Kumar PradhaniD· 1 shared Mingquan Lin· 1 shared Mubashir JafryiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Nian WangORCID

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2 papers

Recent·Most cited

5-HT1A Antagonist WAY-100635 Prevents Chronic Neurodegeneration and Immune Activation After TBI

Sayanta Dutta, Lilesh Kumar Pradhan, Jie Chen, Nian Wang, Xiang Gao, Arupratan Das

This study shows that WAY-100635, a 5-HT1A antagonist, reduces chronic neurodegeneration and immune activation after TBI by preserving neurons, synapses, and visual function.

bioRxiv · Oct 12, 2026 · PreprintNeuroscience

High-resolution MRI Guided Whole Mouse Brain Cell Type Atlas using Deep Learning

Xinyue Han, Rui Hu, Zhuoheng Liu, Jie Chen, Mubashir Jafry, Haoyu Song, Yi Zhao, Mingquan Lin, LEONARD E. WHITE, G. Allan Johnson, Nian Wang

This paper develops a deep learning framework combining high-resolution MRI and spatial transcriptomics to create a whole-brain mouse cell type atlas at 10 micrometer resolution.

bioRxiv · Nov 25, 2025 · PreprintNeuroscience