Microglia are involved in regulating histamine dependent and non-dependent itch transmissions with distinguished signal pathways
Yuxiu Yang, Bin Mou, Qi‐Ruo Zhang, Hong‐Xue Zhao, Jian‐Yun Zhang, Xiao Yun Yun, Mingtao Xiong, Ying Liu, Yong Liu, Haili Pan, Chao‐Lin Ma, Bao‐Ming Li, Jiyun Peng
This study shows that microglia regulate histamine-dependent and non-dependent itch transmission through distinct pathways, with histamine-dependent requiring the CX3CL1-CX3CR1 pathway.
Glia · Jan 1, 2022Peer-reviewedNeuroscience