Shank3 mutation disrupts affective touch encoding in the dorsal medial prefrontal cortex of Beagle dogs
Yanhe Zhou, Yue He, Minna Dan, Lintao Jia, Kun Guo, Ying Fang, Li Hu, Xiang Yu, Jinfen Wang, Dajun Xing, Yongqing Zhang
This study shows that Shank3 mutations in dogs disrupt affective touch processing in the dmPFC, with potential therapeutic implications.
bioRxiv · Sep 5, 2026 · PreprintNeuroscience