Oxaliplatin Inhibits RNA Polymerase I via DNA Damage Signaling Targeted to the Nucleolus
Misha Nechay, Ralph E. Kleiner
This study shows oxaliplatin inhibits RNA polymerase I transcription in the nucleolus through a DNA damage signaling pathway distinct from conventional nucleolar DNA damage responses.
bioRxiv · Apr 2, 2023 · PreprintMolecular Biology