Improving Leukemic CD34+/CD38- Blasts Characterization With Single-Cell Transcriptome Sequencing
Ambra Sartori, Phil Cheng, Emilie Falconnet, Pascale Ribaux, Jean-Pierre Aubry-Lachainaye, Mitchell P. Levesque, Stylianos E. Antonarakis, Thomas Matthes, Christelle Borel
The paper uses single-cell RNA sequencing to analyze leukemic CD34+/CD38- blasts from AML patients, identifying transcriptomic features of self-renewal, mutation effects, and prognostic gene signatures.
bioRxiv · May 31, 2017 · PreprintCancer Biology