Protective Anti-Fibrotic Effect of Liraglutide and Pirfenidone Combination Therapy on Liver Fibrosis in Rats: Effects on Autophagy and NLRP3 Inflammasome
Zeynab Yousefi, Rayan Rajabi, Saeed Karima, Abbas Sahebghadam Lotfi, Mitra Nourbakhsh
This study shows that combining Liraglutide and Pirfenidone reduces liver fibrosis in rats by enhancing autophagy and suppressing NLRP3 inflammasome activation.
BMC Gastroenterology · Dec 18, 2025Peer-reviewedBiochemistry