Collateral sensitivity networks reveal evolutionary instability and novel treatment strategies in ALK mutated non-small cell lung cancer.
Andrew Dhawan, Daniel Nichol, Fumi Kinose, Mohamed E. Abazeed, Andriy Marusyk, Eric B. Haura, Jacob G. Scott
This study shows that resistance to ALK inhibitors in lung cancer is unstable and dynamic, with collateral sensitivity to other drugs offering new treatment options.
Scientific Reports · Apr 27, 2017Peer-reviewedCancer Biology