Multimodal analysis defines GNG4 as a distinguishing feature of germinal center-positioned CD4 T follicular helper cells in humans
Thomas Barnett Dubensky, Yutong Zhu, Molly Gallagher, Kingsley Gideon Kumashie, Tianyu Lu, Jonathan Tedesco, Nina De Luna, Katherine R. Premo, Yi Qi, Suzanna Rachimi, Emylette Cruz Cabrera, Bria Fulmer, Ijeoma C. Meremikwu, Ashley M. Carter, Sarah Emily Henrickson, , Laura A. Vella
The paper identifies GNG4 as a marker for activated CD4 T follicular helper cells in human germinal centers using multimodal single-cell analysis.
bioRxiv · Dec 13, 2025 · PreprintImmunology