Amy E. Baxter

This study decomposes scanner batch effects in pathology foundation models and shows that image corrections based on measured properties improve alignment but do not fully match model representations.

This study evaluates the limits of marker information transfer in cross-panel cytometry imputation, finding that imputation preserves broad lineage classification but not fine-phenotype details, and that patient matching improves cross-platform distribution recovery.

CytoGate-Bench evaluates LLMs for cross-panel cell gating in cytometry by reformulating manual gating as a zero-shot task using expert-annotated data.

The paper develops MAESTRO, a self-supervised deep learning framework to transform immune profiles into embeddings capturing immune health, enabling clinical prediction and precision immunotherapy.

The paper shows that a drug holiday during PD-1 blockade improves reinvigoration of exhausted T cells by restoring progenitor cell function and reducing adaptive resistance.

This study creates a longitudinal multiomic atlas of pediatric high-grade glioma, revealing distinct tumor cell states and therapeutic targets not seen in adult glioblastoma.

The paper identifies GNG4 as a marker for activated CD4 T follicular helper cells in human germinal centers using multimodal single-cell analysis.

The paper identifies TR-TEX cells as distinct from TRM cells, showing they have unique transcriptional regulation and respond differently to PD-1 inhibition.

This study identifies how histone modifications regulate gene expression in memory and exhausted CD8 T cells, revealing distinct epigenetic programs between these cell types.

This study shows that targeting TET2 in CAR T-cells improves their anti-tumor responses by limiting terminal exhaustion and enhancing therapeutic potential.