Potential Role of Nociceptin/Orphanin FQ in the Progression of Multiple Sclerosis
Joseph Carroll Baker, Caitlin E. Paisley, Molly Poore, John W. Bigbee, Unsong Oh, Carmen Sato‐Bigbee
The paper investigates the role of Nociceptin in multiple sclerosis progression, finding elevated levels in severe forms and showing that its receptor antagonist can improve remyelination and reduce neurological dysfunction.
bioRxiv · Jul 22, 2026 · PreprintNeuroscience