Caitlin E. Paisley

The paper investigates the role of Nociceptin in multiple sclerosis progression, finding elevated levels in severe forms and showing that its receptor antagonist can improve remyelination and reduce neurological dysfunction.

The paper shows that phosphatidylserine exposure by developing astrocytes triggers microglia-mediated cell death, leading to vascular defects in the retina and cerebral cortex.

The paper shows that FLRT2-UNC5 signaling mediates synaptic partner rejection in retinal neurons by eliminating dendrites that stray from their correct sublayers.

The paper shows that retinal astrocytes undergo large-scale death during development, mediated by microglia rather than apoptosis, leading to anatomical and functional changes in the retinal network.