Chronic social defeat causes dysregulation of systemic glucose metabolism via the cerebellar fastigial nucleus
Taiga Ishimoto, Takashi Abe, Yuko Nakamura, Tomonori Tsuyama, Kunio Kondoh, Naoto Kajitani, Kaede Yoshida, Yuichi Takeuchi, Kan X. Kato, Shucheng Xu, Maru Koduki, Momoka Ichimura, Takito Itoi, Kenta Shimba, Yoshifumi Yamaguchi, , Chitoku Toda
This study shows chronic social defeat stress in mice causes metabolic dysregulation through cerebellar pathways, linking psychological stress to type II diabetes.
bioRxiv · Feb 18, 2025 · PreprintNeuroscience