The apoptosis gene BCL-X splice isoforms have opposing effects in diabetic kidney disease: potential treatment target and prognostic value
Martin Stevens, Monica Ayine, Kim M. Gooding, Angela C. Shore, P Velbes Marqueti, Sebastian Oltean
The paper investigates the role of BCL-X splice isoforms in diabetic kidney disease, finding that increased BCL-XS promotes apoptosis and correlates with renal function decline, suggesting it as a biomarker and therapeutic target.
Journal of Diabetes Research · Jan 1, 2026Peer-reviewedMolecular Biology