Chlamydia iron starvation links nutritional immunity to pathogen recognition
Monisha R. Alla, Nick D. Pokorzynski, Junghoon Lee, Scot P. Ouellette, Rey A. Carabeo
This study shows that iron starvation of Chlamydia trachomatis increases host recognition of the pathogen by dysregulating a peptidoglycan enzyme, leading to inflammation and cell death.
bioRxiv · Aug 8, 2025 · PreprintMicrobiology