Engineering Infrared Light Detection in Blind Human Retina Using Ultrasensitive Human TRPV1 Channels
Morgan Chevalier, Firas Fadel, Tímea Májer, Dániel Péter Magda, Lili Gerendás, Ferenc Kilin, Zoltán Zsolt Nagy, Arnold Szabó, Botond Roska, Guilherme Testa-Silva
This paper engineers human TRPV1 channels to detect near-infrared light by shifting their temperature sensitivity, enabling light-induced heat activation in retinal cells without immunogenicity issues.
Trends in biotechnology · Aug 29, 2025Peer-reviewedBioengineering