B cell subsets have different capacities for phagocytosis and subsequent presentation of antigen to cognate T cells
Daniel M Morelli, Morgan Langille, Richard Zhang, Heather C. Craig, Ahmed Eltom Mohamed, Parisa Shooshtari, Bryan Heit, Steven M. Kerfoot
The paper investigates phagocytic capacities of B cell subsets and their ability to present antigens to T cells, finding that only peritoneal cavity B1 cells can uptake non-cognate antigens but fail to activate T cells.
The Journal of Immunology · Oct 13, 2025Peer-reviewedImmunology