Steven M. Kerfoot

This study identifies pathogenic autoantibodies in EAE and demonstrates a therapeutic approach using a synthetic antibody to block their activity.

The paper investigates phagocytic capacities of B cell subsets and their ability to present antigens to T cells, finding that only peritoneal cavity B1 cells can uptake non-cognate antigens but fail to activate T cells.

This study identifies transcription factors and cell types involved in gene dysregulation of nine autoimmune diseases using integrative analysis of genetic and chromatin data.