Basal p53 activity is differentially impacted by individual mutations, defining the immediate response to genotoxicity
Maria Jose de la Concha, Patricia Eror Barnes, Kioko Mwikali, Bee Ling Ng, Baisakhi Mondal, Mukund Khatavkar, Hannes Ponstingl, Alena Pance
The paper examines how different p53 mutations affect basal p53 activity and cellular response to genotoxicity in breast cancer cell lines.
bioRxiv · Sep 5, 2024 · PreprintCancer Biology