SARS-CoV-2 selectively mimics a cleavable peptide of human ENaC in a strategic hijack of host proteolytic machinery
Praveen Anand, Arjun Puranik, Murali Aravamudan, AJ Venkatakrishnan, Venky Soundararajan
The paper identifies a SARS-CoV-2 peptide that mimics a human ENaC cleavage site, exploiting host proteolytic machinery and linking it to COVID-19 pathophysiology.
eLife · May 26, 2020Peer-reviewedBioinformatics