Reversal of vein of Galen aneurysmal malformation by stimulation of flow-mediated vessel fusion
Edwige Martin-Valiente, Yao Du, Chloé Goemans, Egor Zindy, Myckel Adam, Benoît Scheid, Miikka Vikkula, Boris Lubicz, Benoît Vanhollebeke, Nicolas Baeyens
This study identifies molecular mechanisms of flow-mediated vessel fusion in zebrafish models of Vein of Galen aneurysmal malformation and demonstrates pharmacological reversal of the malformation.
bioRxiv · Oct 18, 2024 · PreprintDevelopmental Biology