Author

N. Appling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. M. H. Mayfield· 1 shared B. H. Barcelona· 1 shared E. D. Mackey· 1 shared G. M. Coughlin· 1 shared M. Borsos· 1 shared R. A. Eser· 1 shared S. R. Kumar· 1 shared V. Gradinaru· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBioengineering

A. M. H. Mayfield

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1 paper

Recent·Most cited

Spatial genomics of AAVs reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo

G. M. Coughlin, M. Borsos, N. Appling, B. H. Barcelona, A. M. H. Mayfield, E. D. Mackey, R. A. Eser, X. Chen, S. R. Kumar, V. Gradinaru

The paper identifies transcriptional crosstalk between enhancers and promoters delivered by AAVs, showing concatemer formation enables targeted delivery of large genetic cargo for cell-type-specific gene editing.

bioRxiv · Dec 23, 2023Bioengineering